Restless Leg Syndrome (RLS) can be exhausting with nightly disturbance of sleep. A reader of supplements magazine reported having suffered this for many years. At some later point she was then prescribed statins, and decided to also use co-enzyme Q10 to maximise their effectiveness. After starting taking co-enzyme Q10, she found she no longer suffered with RLS. While this is a single instance, it might be worth trying.
Reader's letter to Healthspan magazine, September 2011