Folates occur naturally in many foods, with dark green vegetables a good source.
Low levels in early pregnancy are believed to be the cause of more than half of babies born with neural tube defects. Women may take supplements and more than 80 countries fortify certain foods with folic acid as a precautionary measure.
Folic acid deficiency can cause anaemia. In children this may develop within one month of inadequate dietary intake.
Long term supplementation is associated with some reduction in the risk of stroke and cardiovascular disease. In 2018 it was reported that a new study suggested that a daily 800 microgram dose may significantly reduce the risk of stroke in people with high blood pressure.
Sources: Various